Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 5/20 | 0.41 |
| ▸ | KDM5A | P29375 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29243755 | 0.96 | SMO (0.39) | SMOKDM5AMEN1ALDH1A1KMT2A | |
| SCHEMBL29585960 | 0.95 | SMO (0.44) | SMOKDM5AMEN1ALDH1A1KMT2A | |
| SCHEMBL29243339 | 0.95 | SMO (0.44) | SMOKDM5AMEN1ALDH1A1KMT2A | |
| SCHEMBL29585348 | 0.93 | SMO (0.48) | SMOKDM5AMEN1ALDH1A1KMT2A | |
| SCHEMBL29243721 | 0.93 | SMO (0.48) | SMOKDM5AMEN1ALDH1A1KMT2A | |
| SCHEMBL24424532 | 0.92 | SMO (0.45) | SMOKDM5AMEN1ALDH1A1KMT2A | |
| SCHEMBL29585749 | 0.90 | KDM5A (0.35) | SMOKDM5AMEN1ALDH1A1KMT2A | |
| SCHEMBL29585019 | 0.89 | KDM5A (0.38) | SMOKDM5AMEN1ALDH1A1KMT2A | |
| SCHEMBL29243774 | 0.89 | KDM5A (0.38) | SMOKDM5AMEN1ALDH1A1KMT2A | |
| SCHEMBL29585130 | 0.89 | KDM5A (0.38) | SMOKDM5AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |