Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.57 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26913989 | 1.00 | KMT2A (0.57) | KMT2AMEN1HCAR3KAT2BALDH1A1 | |
| SCHEMBL26913995 | 1.00 | KMT2A (0.57) | KMT2AMEN1HCAR3KAT2BALDH1A1 | |
| SCHEMBL22392063 | 0.90 | MAPT (0.55) | KMT2AMEN1HCAR3KAT2BALDH1A1 | |
| SCHEMBL22392064 | 0.90 | MAPT (0.55) | KMT2AMEN1HCAR3KAT2BALDH1A1 | |
| SCHEMBL5881547 | 0.85 | KAT2B (0.60) | KMT2AMEN1HCAR3KAT2BALDH1A1 | |
| SCHEMBL29585713 | 0.83 | KAT2B (0.53) | KMT2AMEN1HCAR3KAT2BRAB9A | |
| SCHEMBL27171094 | 0.83 | KAT2B (0.53) | KMT2AMEN1HCAR3KAT2BRAB9A | |
| SCHEMBL27171091 | 0.83 | KAT2B (0.53) | KMT2AMEN1HCAR3KAT2BRAB9A | |
| SCHEMBL4464340 | 0.81 | KAT2B (0.56) | KMT2AMEN1HCAR3KAT2BALDH1A1 | |
| SCHEMBL26914073 | 0.81 | KMT2A (0.61) | KMT2AMEN1HCAR3ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229049-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| CN-116547278-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-08-04 | — | — | CN | disclosed |
| WO-2022078380-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-04-21 | — | — | WO | disclosed |