SCHEMBL29586192

SCHEMBL29586192

CCc1c(-c2ccc(O)cc2)cnc(N)c1-c1cccc(CN2CCOCC2)c1

nearest known ligand 0.93

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 20/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18066747 1.00 USP7 (0.93) USP7
SCHEMBL18066751 0.96 USP7 (1.00) USP7
SCHEMBL29586142 0.96 USP7 (1.00) USP7
SCHEMBL29587605 0.85 USP7 (0.68) USP7
SCHEMBL18066739 0.85 USP7 (0.68) USP7
SCHEMBL29586526 0.80 USP7 (0.69) USP7
SCHEMBL18066841 0.80 USP7 (0.69) USP7
SCHEMBL18066801 0.78 USP7 (0.92) USP7
SCHEMBL18066811 0.77 USP7 (0.75) USP7
SCHEMBL29586333 0.77 USP7 (0.75) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531683-B USP7 inhibitor compounds and methods of use 豪夫迈·罗氏有限公司 2022-05-13 CN claimed
CN-107531683-B USP7 inhibitor compounds and methods of use 豪夫迈·罗氏有限公司 2022-05-13 CN disclosed