Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GLI1 | P08151 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29583225 | 0.92 | KMT2A (0.38) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL31614134 | 0.89 | KDM4E (0.44) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL20764925 | 0.87 | KDM4E (0.39) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL29373164 | 0.87 | KDM4E (0.43) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL20765294 | 0.85 | KMT2A (0.38) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL29585583 | 0.83 | TSHR (0.43) | KDM4EKMT2A | |
| SCHEMBL23857824 | 0.81 | KDM4E (0.38) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL31614214 | 0.81 | KDM4E (0.38) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL29585383 | 0.80 | KDM4E (0.35) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL18398649 | 0.78 | KDM4E (0.38) | KDM4EMAPTKMT2AATMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |