Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21326079 | 1.00 | NR1H2 (0.69) | NR1H2ESR2MAPK1HDAC1DDB1 | |
| SCHEMBL21326100 | 0.95 | ESR2 (0.70) | NR1H2ESR2MAPK1HDAC1DDB1 | |
| SCHEMBL29587366 | 0.95 | ESR2 (0.70) | NR1H2ESR2MAPK1HDAC1DDB1 | |
| SCHEMBL38653719 | 0.89 | ESR2 (0.54) | NR1H2ESR2MAPK1HDAC1DDB1 | |
| SCHEMBL23253904 | 0.89 | ESR2 (0.54) | NR1H2ESR2MAPK1HDAC1DDB1 | |
| SCHEMBL31335550 | 0.85 | NR1H2 (0.60) | NR1H2ESR2MAPK1HDAC1DDB1 | |
| SCHEMBL17813389 | 0.84 | ESR2 (0.69) | NR1H2ESR2MAPK1HDAC1DDB1 | |
| SCHEMBL12252190 | 0.83 | NR1H2 (0.74) | NR1H2ESR2MAPK1HDAC1DDB1 | |
| SCHEMBL545619 | 0.83 | ESR2 (0.90) | NR1H2ESR2MAPK1HDAC1DDB1 | |
| SCHEMBL29372093 | 0.83 | ESR2 (0.90) | NR1H2ESR2MAPK1HDAC1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026099404-A1 | SULFONYLUREA DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER | QUBIT PHARMACEUTICALS (FR) | 2026-05-15 | — | — | WO | disclosed |
| EP-4741375-A1 | SULFONYLUREA DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER | Qubit Pharmaceuticals (FR) | 2026-05-13 | — | — | EP | disclosed |
| CN-109863145-B | Novel tetrahydroisoquinoline and tetrahydronaphthyridine compounds for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2022-04-12 | — | — | CN | disclosed |