Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | GOT1 | P17174 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12089089 | 0.83 | CYP1A2 (0.53) | CYP1A2CTDSP1NLRP3GOT1CHRM1 | |
| SCHEMBL7986678 | 0.80 | CYP1A2 (0.54) | CYP1A2CTDSP1NLRP3GOT1CHRM1 | |
| SCHEMBL24923647 | 0.78 | CYP1A2 (0.49) | CYP1A2CTDSP1NLRP3GOT1CHRM1 | |
| SCHEMBL28844933 | 0.74 | CYP1A2 (0.49) | CYP1A2CTDSP1NLRP3GOT1CHRM1 | |
| SCHEMBL14167266 | 0.74 | CYP1A2 (0.49) | CYP1A2CTDSP1NLRP3GOT1HRH1 | |
| SCHEMBL14167452 | 0.74 | CYP1A2 (0.57) | CYP1A2CTDSP1NLRP3VNN1P2RX7 | |
| SCHEMBL9318794 | 0.73 | GRIN2D (0.56) | CYP1A2HRH1GRIN1GRIN2BGRIN2D | |
| SCHEMBL4685897 | 0.73 | GRIN2D (0.56) | CYP1A2HRH1GRIN1GRIN2BGRIN2D | |
| SCHEMBL14167085 | 0.72 | CTDSP1 (0.42) | CYP1A2CTDSP1NLRP3GOT1CHRM1 | |
| SCHEMBL8862816 | 0.72 | GRIN2D (0.64) | CYP1A2CTDSP1VNN1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727782-B1 | METHOD OF PRODUCING AMINOPHENOL COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 2012-08-22 | — | — | EP | disclosed |
| US-7750156-B2 | Method of producing aminophenol compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-07-06 | — | — | US | disclosed |
| CN-100478325-C | Preparation method for aminophenol compound | OTSUKA PHARMA CO LTD (JP) | 2009-04-15 | — | — | CN | disclosed |
| US-20070219374-A1 | Method of Producing Aminophenol Compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| CN-1938261-A | Preparation method for aminophenol compound | OTSUKA PHARMA CO LTD (JP) | 2007-03-28 | — | — | CN | disclosed |
| EP-1727782-A1 | METHOD OF PRODUCING AMINOPHENOL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005092832-A1 | METHOD OF PRODUCING AMINOPHENOL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219374-A1 | Method of Producing Aminophenol Compounds | PAH, CYP1A1, CYP1B1 | CYP1A2 8/4885CTDSP1 1795/4885NLRP3 2259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.