Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 10/20 | 0.45 |
| ▸ | F9 | P00740 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12911867 | 0.89 | TRPV1 (0.45) | TRPV1F10F9KDM4EMAPT | |
| SCHEMBL950828 | 0.89 | TRPV1 (0.45) | TRPV1F10F9KDM4EMAPT | |
| SCHEMBL12911593 | 0.87 | TRPV1 (0.44) | TRPV1F10F9KDM4EMAPT | |
| SCHEMBL12911883 | 0.87 | TRPV1 (0.43) | TRPV1F10F9KDM4EMAPT | |
| SCHEMBL951228 | 0.87 | TRPV1 (0.43) | TRPV1F10F9KDM4EMAPT | |
| SCHEMBL13072905 | 0.86 | TRPV1 (0.43) | TRPV1F10F9KDM4EALDH1A1 | |
| SCHEMBL27727973 | 0.86 | TRPV1 (0.43) | TRPV1F10F9KDM4EMAPT | |
| SCHEMBL13318531 | 0.85 | F10 (0.46) | TRPV1F10F9KDM4EKLKB1 | |
| SCHEMBL12911609 | 0.84 | TRPV1 (0.42) | TRPV1F10F9KDM4EMAPT | |
| SCHEMBL27727859 | 0.84 | TRPV1 (0.41) | TRPV1F10F9KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754738-B2 | Pyrazole and pyrrole carboxamide insecticides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-13 | — | — | US | disclosed |
| US-20060167060-A1 | Pyrazole and pyrrole carboxamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167060-A1 | Pyrazole and pyrrole carboxamide insecticides | CBR3, C1S, CBR1 | TRPV1 698/4885F10 1147/4885F9 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.