Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440123 | 0.98 | RET (0.58) | RETLCKSRC | |
| SCHEMBL19732705 | 0.85 | RET (0.61) | RET | |
| SCHEMBL19303914 | 0.82 | RET (0.64) | RET | |
| SCHEMBL29588931 | 0.81 | RET (0.60) | RETLCKSRC | |
| SCHEMBL19732745 | 0.81 | RET (0.63) | RET | |
| SCHEMBL29589133 | 0.80 | RET (0.61) | RETLCKSRC | |
| SCHEMBL19732673 | 0.77 | RET (0.63) | RETLCKSRC | |
| SCHEMBL29589208 | 0.77 | RET (0.57) | RETLCKSRC | |
| SCHEMBL19732685 | 0.77 | RET (0.42) | RETLCKSRC | |
| SCHEMBL19732675 | 0.77 | RET (0.62) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108697714-B | Fused pyrimidine compound or salt thereof | 大鹏药品工业株式会社 | 2022-04-26 | — | — | CN | disclosed |