Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.68 |
| ▸ | KDR | P35968 | 7/20 | 0.68 |
| ▸ | RET | P07949 | 2/20 | 0.68 |
| ▸ | JAK2 | O60674 | 2/20 | 0.68 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.68 |
| ▸ | CDK1 | P06493 | 2/20 | 0.68 |
| ▸ | ROS1 | P08922 | 2/20 | 0.68 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.68 |
| ▸ | CDK2 | P24941 | 2/20 | 0.68 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.68 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.68 |
| ▸ | CLK2 | P49760 | 2/20 | 0.68 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.68 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.68 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.68 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.68 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.68 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.68 |
| ▸ | CDC7 | O00311 | 1/20 | 0.68 |
| ▸ | PLK4 | O00444 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732801 | 1.00 | SRC (0.68) | SRCKDRRETJAK2DYRK3 | |
| SCHEMBL24096480 | 0.87 | JAK2 (0.86) | SRCKDRRETJAK2DYRK3 | |
| SCHEMBL19732645 | 0.87 | SRC (0.68) | SRCKDRRETJAK2DYRK3 | |
| SCHEMBL24096505 | 0.86 | SRC (0.64) | SRCKDRRETJAK2DYRK3 | |
| SCHEMBL1318717 | 0.85 | SRC (0.77) | SRCKDRRETJAK2DYRK3 | |
| SCHEMBL401336 | 0.85 | KDR (0.77) | SRCKDRRETJAK2DYRK3 | |
| SCHEMBL19304165 | 0.84 | SRC (0.48) | SRCKDRRETJAK2DYRK3 | |
| SCHEMBL5805110 | 0.84 | RET (0.64) | SRCKDRRETJAK2DYRK3 | |
| SCHEMBL23847456 | 0.83 | KDR (0.75) | SRCKDRRETJAK2DYRK3 | |
| SCHEMBL4826075 | 0.82 | KDR (0.78) | SRCKDRRETJAK2DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108697714-B | Fused pyrimidine compound or salt thereof | 大鹏药品工业株式会社 | 2022-04-26 | — | — | CN | disclosed |