Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAF1 | P04049 | 17/20 | 0.52 |
| ▸ | BRAF | P15056 | 17/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14784324 | 1.00 | KDM4E (0.56) | KDM4EGAARAF1BRAFWDR5 | |
| SCHEMBL14783117 | 0.91 | HDAC3 (0.50) | KDM4EGAARAF1BRAF | |
| SCHEMBL29590152 | 0.91 | HDAC3 (0.50) | KDM4EGAARAF1BRAF | |
| SCHEMBL29590150 | 0.89 | IDH2 (0.49) | KDM4EGAARAF1BRAF | |
| SCHEMBL14783124 | 0.89 | IDH2 (0.49) | KDM4EGAARAF1BRAF | |
| SCHEMBL14783093 | 0.89 | RAF1 (0.55) | KDM4EGAARAF1BRAF | |
| SCHEMBL14783841 | 0.87 | BRAF (0.44) | KDM4EGAARAF1BRAF | |
| SCHEMBL29590197 | 0.87 | BRAF (0.44) | KDM4EGAARAF1BRAF | |
| SCHEMBL15689264 | 0.86 | RAF1 (0.57) | KDM4EGAARAF1BRAF | |
| SCHEMBL16507059 | 0.86 | KDM4E (0.54) | KDM4EGAARAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |