Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 11/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14784050 | 1.00 | MTOR (0.51) | MTORPIK3CAPIK3CGKCNQ3KCNQ2 | |
| SCHEMBL29591439 | 0.94 | MTOR (0.51) | MTORPIK3CAPIK3CGKCNQ3KCNQ2 | |
| SCHEMBL29590351 | 0.94 | KCNQ3 (0.46) | MTORPIK3CAPIK3CGKCNQ3KCNQ2 | |
| SCHEMBL14782812 | 0.94 | KCNQ3 (0.46) | MTORPIK3CAPIK3CGKCNQ3KCNQ2 | |
| SCHEMBL14783581 | 0.94 | MTOR (0.51) | MTORPIK3CAPIK3CGKCNQ3KCNQ2 | |
| SCHEMBL14783011 | 0.94 | MTOR (0.52) | MTORPIK3CAPIK3CGKCNQ3KCNQ2 | |
| SCHEMBL29591549 | 0.94 | MTOR (0.52) | MTORPIK3CAPIK3CGKCNQ3KCNQ2 | |
| SCHEMBL29591622 | 0.93 | KCNQ3 (0.55) | KCNQ3KCNQ2HDAC3TP53MAPT | |
| SCHEMBL14783318 | 0.93 | KCNQ3 (0.55) | KCNQ3KCNQ2HDAC3TP53MAPT | |
| SCHEMBL15688579 | 0.93 | MTOR (0.51) | MTORPIK3CAPIK3CGKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |