Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 13/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 13/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 13/20 | 0.44 |
| ▸ | KDR | P35968 | 12/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 11/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | ILK | Q13418 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27090893 | 1.00 | MAPK1 (0.52) | MAPK1FGFR1FGFR2FGFR3KDR | |
| SCHEMBL2592957 | 0.94 | MAPK1 (0.52) | MAPK1FGFR1FGFR2FGFR3KDR | |
| SCHEMBL29400331 | 0.82 | TLR9 (0.63) | MAPK1FGFR1FGFR2FGFR3KDR | |
| SCHEMBL30646549 | 0.82 | MAPK1 (0.52) | MAPK1FGFR1FGFR2FGFR3KDR | |
| SCHEMBL7600391 | 0.80 | TLR9 (0.51) | KDRFLT3TLR9 | |
| SCHEMBL29590784 | 0.79 | MAPK1 (0.59) | MAPK1FGFR1FGFR2FGFR3KDR | |
| SCHEMBL5211835 | 0.79 | MAPK1 (0.59) | MAPK1FGFR1FGFR2FGFR3KDR | |
| SCHEMBL5199018 | 0.78 | TLR9 (0.66) | MAPK1KDRFLT3TLR9 | |
| SCHEMBL12178898 | 0.76 | TLR9 (0.55) | MAPK1FGFR1FGFR2FGFR3KDR | |
| SCHEMBL16642057 | 0.76 | MAPK1 (0.52) | MAPK1FGFR1FGFR2FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225749-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | Cullgen (Shanghai), Inc. (CN) | 2023-08-16 | — | — | EP | disclosed |
| CN-116583509-A | Compounds and methods for treating cancer | 上海睿跃生物科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |