Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27091090 | 1.00 | CRBN (0.56) | CRBNIKZF2 | |
| SCHEMBL29094767 | 0.87 | CRBN (0.62) | CRBN | |
| SCHEMBL29440022 | 0.85 | CRBN (0.58) | CRBN | |
| SCHEMBL22512119 | 0.85 | CRBN (0.58) | CRBN | |
| SCHEMBL20913657 | 0.85 | CRBN (0.62) | CRBN | |
| SCHEMBL21759455 | 0.83 | CRBN (0.67) | CRBN | |
| SCHEMBL30128254 | 0.83 | CRBN (0.67) | CRBN | |
| SCHEMBL26270745 | 0.83 | CRBN (0.64) | CRBNIKZF2 | |
| SCHEMBL24289050 | 0.83 | CRBN (0.59) | CRBNIKZF2 | |
| SCHEMBL23298772 | 0.81 | CRBN (0.63) | CRBNIKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225749-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | Cullgen (Shanghai), Inc. (CN) | 2023-08-16 | — | — | EP | disclosed |
| CN-116583509-A | Compounds and methods for treating cancer | 上海睿跃生物科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |