Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 19/20 | 0.57 |
| ▸ | BRAF | P15056 | 19/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783381 | 1.00 | RAF1 (0.57) | RAF1BRAFKDM4EGAA | |
| SCHEMBL15689264 | 0.94 | RAF1 (0.57) | RAF1BRAFKDM4EGAA | |
| SCHEMBL14783093 | 0.92 | RAF1 (0.55) | RAF1BRAFKDM4EGAA | |
| SCHEMBL14783483 | 0.92 | RAF1 (0.49) | RAF1BRAF | |
| SCHEMBL29590204 | 0.92 | RAF1 (0.49) | RAF1BRAF | |
| SCHEMBL14784012 | 0.91 | MAPT (0.52) | RAF1BRAFGAA | |
| SCHEMBL29590175 | 0.91 | MAPT (0.52) | RAF1BRAFGAA | |
| SCHEMBL15689028 | 0.90 | RAF1 (0.59) | RAF1BRAFKDM4EGAA | |
| SCHEMBL14782951 | 0.90 | BRAF (0.59) | RAF1BRAFKDM4EGAA | |
| SCHEMBL14783103 | 0.89 | KCNQ3 (0.63) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |