SCHEMBL2959136

SCHEMBL2959136

c1ccc(CO[SiH](OCc2ccccc2)OCc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
IDO1 P14902 1/20 0.52
AGXT P21549 1/20 0.50
MAOB P27338 2/20 0.43
ALDH1A1 P00352 3/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A3 Q01959 2/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
PTGS1 P23219 1/20 0.43
CYP2C19 P33261 1/20 0.43
PTGS2 P35354 1/20 0.43
HIF1A Q16665 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
CALM1 P0DP23 1/20 0.43
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18297922 0.89 TSHR (0.46) TSHRIDO1AGXTMAOBALDH1A1
SCHEMBL838793 0.89 TSHR (0.46) TSHRIDO1AGXTMAOBALDH1A1
SCHEMBL7056374 0.85 TSHR (0.48) TSHRIDO1AGXTMAOBALDH1A1
SCHEMBL18297894 0.85 TSHR (0.48) TSHRIDO1AGXTMAOBALDH1A1
SCHEMBL18297890 0.84 TSHR (0.46) TSHRIDO1AGXTMAOBSLC6A2
SCHEMBL18297907 0.84 TSHR (0.46) TSHRIDO1AGXTMAOBSLC6A2
SCHEMBL5524047 0.83 LCK (0.50) TSHRMAOBCA9LMNACYP1A2
SCHEMBL18297935 0.82 TSHR (0.44) TSHRIDO1AGXTMAOBALDH1A1
SCHEMBL19809146 0.80 CETP (0.44) TSHRALDH1A1L3MBTL1MAPK1TDP1
SCHEMBL18297901 0.80 TSHR (0.43) TSHRIDO1AGXTALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0528496-A2 Polymerization of cycloolefins and catalytic system suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-02-24 EP claimed
WO-2023054730-A1 SOLAR CELL MODULE INSULATION FILM, INSULATION FILM WITH STEEL SHEET, INSULATION FILM WITH WIRING SHEET, AND SOLAR CELL MODULE 大日本印刷株式会社 2023-04-06 WO disclosed
WO-2023286859-A1 SOLAR-CELL-MODULE SEALANT SHEET, SOLAR-CELL-MODULE SEALANT COMPOSITION, AND SOLAR CELL MODULE 大日本印刷株式会社 2023-01-19 WO disclosed
EP-3103805-B1 SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND AIST (JP) 2020-11-18 EP disclosed
US-10308670-B2 Silanol compound, composition, and method for producing silanol compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-04 US disclosed
US-20170183363-A1 Silanol Compound, Composition, and Method for Producing Silanol Compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-06-29 US disclosed
EP-3103805-A1 SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND National Institute of Advanced Industrial Science and Technology (JP) 2016-12-14 EP disclosed
US-7829254-B2 Non-magnetic toner, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2010-11-09 US disclosed
US-7803958-B2 Crosslinkers containing silane BASF COATINGS GMBH (DE) 2010-09-28 US disclosed
US-7772333-B2 Film-forming material containing resin with -Si(OR)3 and crosslinkable groups BASF COATINGS GMBH (DE) 2010-08-10 US disclosed
US-7714068-B2 Coating compositions containing silane, methods for producing a coating composition and a coated substrate BASF COATINGS GMBH (DE) 2010-05-11 US disclosed
EP-2152825-A2 FILM-FORMING MATERIAL, CROSSLINKERS AND COATING COMPOSITIONS CONTAINING SILANE, METHODS FOR PRODUCING A COATING COMPOSITION AND A COATED SUBSTRATE BASF Corporation (US) 2010-02-17 EP disclosed
WO-2009045558-A2 FILM-FORMING MATERIAL, CROSSLINKERS AND COATING COMPOSITIONS CONTAINING SILANE, METHODS FOR PRODUCING A COATING COMPOSITION AND A COATED SUBSTRATE BASF CORPORATION (US) 2009-04-09 WO disclosed
US-20080248211-A1 COATING COMPOSITIONS CONTAINING SILANE, METHODS FOR PRODUCING A COATING COMPOSITION AND A COATED SUBSTRATE BASF CORPORATION (US) 2008-10-09 US disclosed
US-20080223255-A1 FILM-FORMING MATERIAL CONTAINING SILANE BASF CORPORATION (US) 2008-09-18 US disclosed
US-20080227926-A1 CROSSLINKERS CONTAINING SILANE BASF CORPORATION (US) 2008-09-18 US disclosed
US-20070218388-A1 NON-MAGNETIC TONER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-09-20 US disclosed
US-5344804-A Tungsten compound with silane and boron halide for catalytic polymerization SHELL RESEARCH LIMITED (GB) 1994-09-06 US disclosed
EP-0528496-A2 Polymerization of cycloolefins and catalytic system suitable for use therein SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-02-24 EP disclosed
US-4257932-A CHAIN STOPPED POLYSILOXANE, FLUID POLYSILOXANE-SILICATE AND A CROSSLINKING AGENT; MOISTURE CURABLE TO FORM GASKETS GENERAL ELECTRIC COMPANY (US) 1981-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170183363-A1 Silanol Compound, Composition, and Method for Producing Silanol Compound LSS, MSMO1, ALG3 TSHR 4865/4885IDO1 3463/4885AGXT 3335/4885
US-10308670-B2 Silanol compound, composition, and method for producing silanol compound LSS, MSMO1, ALG3 TSHR 4865/4885IDO1 3463/4885AGXT 3335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.