Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783330 | 1.00 | NPC1 (0.50) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL14783055 | 0.92 | KMT2A (0.55) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL29591543 | 0.92 | KMT2A (0.55) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL14782817 | 0.91 | KMT2A (0.52) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL29591731 | 0.91 | KMT2A (0.52) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL29591960 | 0.91 | KMT2A (0.54) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL14782961 | 0.91 | KMT2A (0.54) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL14783147 | 0.90 | MEN1 (0.55) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL29590210 | 0.90 | MEN1 (0.55) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL29590516 | 0.89 | SMN1; SMN2 (0.53) | NPC1MEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |