Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 7/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783339 | 1.00 | MAPT (0.46) | MAPTTP53SMN1; SMN2CNR1KCNQ3 | |
| SCHEMBL14783348 | 0.92 | PIK3CA (0.48) | KCNQ3KCNQ2HDAC3NPC1RAB9A | |
| SCHEMBL29590717 | 0.92 | PIK3CA (0.48) | KCNQ3KCNQ2HDAC3NPC1RAB9A | |
| SCHEMBL29590369 | 0.92 | HDAC3 (0.51) | MAPTTP53SMN1; SMN2CNR1HDAC3 | |
| SCHEMBL14784095 | 0.92 | HDAC3 (0.51) | MAPTTP53SMN1; SMN2CNR1HDAC3 | |
| SCHEMBL29590313 | 0.92 | MAPT (0.48) | MAPTTP53SMN1; SMN2CNR1KCNQ3 | |
| SCHEMBL14783015 | 0.92 | MAPT (0.48) | MAPTTP53SMN1; SMN2CNR1KCNQ3 | |
| SCHEMBL14783382 | 0.91 | MAPT (0.43) | MAPTTP53SMN1; SMN2CNR1HDAC3 | |
| SCHEMBL29590307 | 0.91 | MAPT (0.43) | MAPTTP53SMN1; SMN2CNR1HDAC3 | |
| SCHEMBL14784252 | 0.91 | KCNQ3 (0.49) | MAPTTP53SMN1; SMN2CNR1KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |