Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783653 | 1.00 | CNR1 (0.48) | CNR1FAAHCNR2TP53LMNA | |
| SCHEMBL14783168 | 0.93 | CNR1 (0.48) | CNR1FAAHCNR2TP53LMNA | |
| SCHEMBL29590279 | 0.93 | CNR1 (0.48) | CNR1FAAHCNR2TP53LMNA | |
| SCHEMBL29590185 | 0.92 | HDAC3 (0.47) | CNR1TP53LMNAMEN1KMT2A | |
| SCHEMBL14783652 | 0.92 | PIK3CA (0.47) | TP53LMNAMEN1KMT2AHTT | |
| SCHEMBL29590182 | 0.92 | PIK3CA (0.47) | TP53LMNAMEN1KMT2AHTT | |
| SCHEMBL14783640 | 0.92 | HDAC3 (0.47) | CNR1TP53LMNAMEN1KMT2A | |
| SCHEMBL14783392 | 0.92 | CNR1 (0.50) | CNR1FAAHCNR2TP53LMNA | |
| SCHEMBL29590675 | 0.92 | CNR1 (0.50) | CNR1FAAHCNR2TP53LMNA | |
| SCHEMBL14783731 | 0.91 | MCHR1 (0.42) | CNR1TP53LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |