Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.80 |
| ▸ | PIK3CA | P42336 | 19/20 | 0.80 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.69 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2278174 | 1.00 | MTOR (0.80) | MTORPIK3CAPIK3CDPIK3CG | |
| SCHEMBL2281483 | 0.89 | MTOR (1.00) | MTORPIK3CAPIK3CDPIK3CG | |
| SCHEMBL2286540 | 0.89 | MTOR (0.81) | MTORPIK3CA | |
| SCHEMBL2285051 | 0.88 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL2283513 | 0.88 | MTOR (1.00) | MTORPIK3CAPIK3CDPIK3CG | |
| SCHEMBL2282553 | 0.88 | PIK3CA (1.00) | MTORPIK3CAPIK3CDPIK3CG | |
| SCHEMBL2283506 | 0.88 | MTOR (1.00) | MTORPIK3CAPIK3CDPIK3CG | |
| SCHEMBL2284633 | 0.88 | PIK3CA (1.00) | MTORPIK3CA | |
| SCHEMBL2282217 | 0.87 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL2284431 | 0.86 | MTOR (0.81) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047008-A1 | HSP90-BINDING CONJUGATES AND FORMULATIONS THEREOF | TARVEDA THERAPEUTICS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |