Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 3/20 | 0.63 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783103 | 1.00 | KCNQ3 (0.63) | KCNQ3KCNQ2LMNATSHRMAPT | |
| SCHEMBL29591294 | 0.93 | KCNQ3 (0.54) | KCNQ3KCNQ2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL14783014 | 0.93 | KCNQ3 (0.54) | KCNQ3KCNQ2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL14783318 | 0.93 | KCNQ3 (0.55) | KCNQ3KCNQ2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29591622 | 0.93 | KCNQ3 (0.55) | KCNQ3KCNQ2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29591304 | 0.92 | KCNQ3 (0.53) | KCNQ3KCNQ2LMNATSHRMAPT | |
| SCHEMBL14783922 | 0.92 | KCNQ3 (0.53) | KCNQ3KCNQ2LMNATSHRMAPT | |
| SCHEMBL14784100 | 0.92 | MAPT (0.57) | KCNQ3KCNQ2LMNATSHRMAPT | |
| SCHEMBL29591524 | 0.92 | MAPT (0.57) | KCNQ3KCNQ2LMNATSHRMAPT | |
| SCHEMBL14783011 | 0.92 | MTOR (0.52) | KCNQ3KCNQ2DGAT1CDK6MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |