Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Carbenicillin Indanyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TEK | Q02763 | 1/20 | 0.57 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | CCKBR | P32239 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 6/20 | 0.51 |
| ▸ | CA2 | P00918 | 6/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbenicillin Indanyl SCHEMBL33855 | 1.00 | KDM4E (0.57) | KDM4ERECQLTDP1MEN1KMT2A | |
| Carbenicillin Indanyl SCHEMBL4936924 | 1.00 | KDM4E (0.57) | KDM4ERECQLTDP1MEN1KMT2A | |
| Carbenicillin Indanyl SCHEMBL33857 | 1.00 | KDM4E (0.57) | KDM4ERECQLTDP1MEN1KMT2A | |
| Carbenicillin Indanyl SCHEMBL11309244 | 1.00 | KDM4E (0.57) | KDM4ERECQLTDP1MEN1KMT2A | |
| Carbenicillin Indanyl SCHEMBL10741454 | 1.00 | KDM4E (0.57) | KDM4ERECQLTDP1MEN1KMT2A | |
| Carbenicillin Indanyl SCHEMBL22818119 | 0.99 | KDM4E (0.56) | KDM4ERECQLTDP1MEN1KMT2A | |
| Carbenicillin Indanyl SCHEMBL954017 | 0.99 | KDM4E (0.56) | KDM4ERECQLTDP1MEN1KMT2A | |
| Carbenicillin Indanyl SCHEMBL11311104 | 0.99 | KDM4E (0.56) | KDM4ERECQLTDP1MEN1KMT2A | |
| Carbenicillin Indanyl SCHEMBL15668574 | 0.98 | PTGS1 (0.56) | KDM4ERECQLTDP1MEN1KMT2A | |
| Carbenicillin Indanyl SCHEMBL1736359 | 0.97 | PTGS1 (0.55) | KDM4ERECQLTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3139930-B1 | SALTS AND POLYMORPHS OF CYCLIC BORONIC ACID ESTER DERIVATIVES AND THERAPEUTIC USES THEREOF | MELINTA THERAPEUTICS INC (US) | 2024-08-14 | — | — | EP | claimed |
| EP-3849562-B1 | COMBINATION COMPOSITIONS COMPRISING A BETA-LACTAMASE INHIBITOR | VENATORX PHARMACEUTICALS INC (US) | 2024-06-26 | — | — | EP | claimed |
| EP-3781576-B1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA INC (US) | 2024-06-12 | — | — | EP | claimed |
| EP-3122757-B1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO LTD (CN) | 2023-09-06 | — | — | EP | claimed |
| EP-3986476-A1 | A FORMULATION OF A CONJUGATE OF A TUBULYSIN ANALOG TO A CELL-BINDING MOLECULE | Hangzhou Dac Biotech Co., Ltd. (CN) | 2022-04-27 | — | — | EP | claimed |
| WO-2022074541-A1 | CANNABINOID-CONTAINING COMPOSITIONS AND USE FOR TREATING AND PREVENTING DISEASES | Max Biology Co. Ltd. (KH) | 2022-04-14 | — | — | WO | disclosed |