Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22939319 | 1.00 | SYK (0.39) | SYKL3MBTL1ATRCA1CA2 | |
| SCHEMBL19738337 | 0.86 | SYK (0.39) | SYKL3MBTL1ATRLCKMAPT | |
| SCHEMBL19738205 | 0.86 | SYK (0.39) | SYKL3MBTL1ATRMAPTTDP1 | |
| SCHEMBL19738338 | 0.86 | SYK (0.37) | SYKL3MBTL1ATRMAPTTDP1 | |
| SCHEMBL19738339 | 0.85 | SYK (0.39) | SYKL3MBTL1ATRCA1CA2 | |
| SCHEMBL29124868 | 0.84 | SYK (0.38) | SYKL3MBTL1ATRMAPTTDP1 | |
| SCHEMBL29124870 | 0.83 | SYK (0.37) | SYKL3MBTL1ATRMAPTTDP1 | |
| SCHEMBL24653331 | 0.81 | AURKA (0.40) | SYKL3MBTL1ATRCA1CA2 | |
| SCHEMBL29124862 | 0.80 | SYK (0.36) | SYKL3MBTL1MAPTTDP1 | |
| SCHEMBL16146754 | 0.80 | GDA (0.39) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003369-A1 | ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Brii Biosciences, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| CN-114502175-A | Adenosine derivatives and pharmaceutical compositions containing the same | 腾盛博药生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |