Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 6/20 | 0.47 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.44 |
| ▸ | PAK4 | O96013 | 2/20 | 0.44 |
| ▸ | PAK3 | O75914 | 1/20 | 0.43 |
| ▸ | PAK2 | Q13177 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | YES1 | P07947 | 1/20 | 0.43 |
| ▸ | HCK | P08631 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26576047 | 1.00 | IGF1R (0.47) | IGF1RNEK1SRCPAK1PAK4 | |
| SCHEMBL25242057 | 1.00 | IGF1R (0.47) | IGF1RNEK1SRCPAK1PAK4 | |
| SCHEMBL29594362 | 0.97 | IGF1R (0.45) | IGF1RNEK1SRCPAK1PAK4 | |
| SCHEMBL25292486 | 0.97 | IGF1R (0.45) | IGF1RNEK1SRCPAK1PAK4 | |
| SCHEMBL29592987 | 0.93 | NEK1 (0.46) | IGF1RNEK1SRCPAK1PAK4 | |
| SCHEMBL25240444 | 0.93 | NEK1 (0.46) | IGF1RNEK1SRCPAK1PAK4 | |
| SCHEMBL26576065 | 0.93 | NEK1 (0.46) | IGF1RNEK1SRCPAK1PAK4 | |
| SCHEMBL24065154 | 0.91 | IGF1R (0.48) | IGF1RNEK1SRCPAK1PAK4 | |
| SCHEMBL29594449 | 0.87 | IGF1R (0.45) | IGF1RNEK1SRCPAK1PAK4 | |
| SCHEMBL25288416 | 0.87 | IGF1R (0.45) | IGF1RNEK1SRCPAK1PAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204411-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | Nalo Therapeutics (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022046861-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2022-03-03 | — | — | WO | disclosed |