Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.75 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.66 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.66 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312076 | 1.00 | HSP90AA1 (0.75) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL13539716 | 0.90 | HSP90AA1 (0.79) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL3799848 | 0.90 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL3794134 | 0.89 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL13539617 | 0.88 | HSP90AA1 (0.79) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL12614326 | 0.88 | HSP90AA1 (0.75) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL5546277 | 0.88 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL10236774 | 0.87 | HSP90AA1 (0.78) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL13539442 | 0.87 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1TRAP1HSP90B1 | |
| SCHEMBL3393574 | 0.86 | HSP90AA1 (0.72) | HSP90AA1HSP90AB1TRAP1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047008-A1 | HSP90-BINDING CONJUGATES AND FORMULATIONS THEREOF | TARVEDA THERAPEUTICS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |