Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.53 |
| ▸ | GSK3A | P49840 | 15/20 | 0.53 |
| ▸ | PRKCB | P05771 | 6/20 | 0.53 |
| ▸ | CDK4 | P11802 | 6/20 | 0.53 |
| ▸ | CDK2 | P24941 | 5/20 | 0.53 |
| ▸ | CAMK2G | Q13555 | 3/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.53 |
| ▸ | PRKCG | P05129 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 2/20 | 0.53 |
| ▸ | CDK1 | P06493 | 2/20 | 0.53 |
| ▸ | PIM1 | P11309 | 2/20 | 0.53 |
| ▸ | CLK2 | P49760 | 2/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.53 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.53 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29594123 | 0.91 | GSK3B (0.64) | GSK3BGSK3APRKCBCDK4CDK2 | |
| SCHEMBL29594479 | 0.90 | GSK3B (0.56) | GSK3BGSK3APRKCBCDK4CDK2 | |
| SCHEMBL29593733 | 0.89 | GSK3B (0.63) | GSK3BGSK3APRKCBCDK4CDK2 | |
| SCHEMBL29534245 | 0.89 | GSK3B (0.68) | GSK3BGSK3APRKCBCDK4CDK2 | |
| SCHEMBL21577580 | 0.89 | GSK3B (0.68) | GSK3BGSK3APRKCBCDK4CDK2 | |
| SCHEMBL20439154 | 0.87 | GSK3B (0.56) | GSK3BGSK3APRKCBCDK4CDK2 | |
| SCHEMBL22510713 | 0.87 | GSK3B (0.52) | GSK3BGSK3APRKCBCDK4CDK2 | |
| SCHEMBL22510694 | 0.87 | GSK3B (0.52) | GSK3BGSK3APRKCBCDK4CDK2 | |
| SCHEMBL20439165 | 0.87 | GSK3B (0.56) | GSK3BGSK3APRKCBCDK4CDK2 | |
| SCHEMBL29593130 | 0.87 | GSK3B (0.51) | GSK3BGSK3APRKCBCDK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114340611-A | Combination of CHIR99021 and valproic acid for the treatment of hearing loss | 频率医疗公司 | 2022-04-12 | — | — | CN | disclosed |