Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378942 | 0.69 | — | — | |
| SCHEMBL30726721 | 0.69 | — | — | |
| SCHEMBL30726769 | 0.67 | — | — | |
| SCHEMBL30627438 | 0.62 | — | — | |
| SCHEMBL30627437 | 0.62 | — | — | |
| SCHEMBL30726736 | 0.60 | — | — | |
| SCHEMBL30726743 | 0.56 | CYP1A2 (0.31) | — | |
| SCHEMBL20780500 | 0.56 | CA1 (0.39) | MAPTBLM | |
| SCHEMBL15557655 | 0.56 | MAPT (1.00) | MAPTIDO1GAAKDM1AKDM4E | |
| SCHEMBL26707331 | 0.55 | TDP1 (0.35) | MAPTGAAKDM4EABL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023207921-A1 | TAXAMAIRIN ANALOGS AND METHODS OF PREPARATION AND USE THEREOF | HONG KONG BAPTIST UNIVERSITY (CN) | 2023-11-02 | — | — | WO | disclosed |
| CN-114591277-B | 5/6/7/6 tetracyclic compound fused with benzene ring and synthetic method thereof | 南京林业大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-114591277-A | 5/6/7/6 tetracyclic compound fused with benzene ring and synthesis method thereof | 南京林业大学 | 2022-06-07 | — | — | CN | disclosed |