⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118865 | 1.00 | — | — | |
| SCHEMBL28838630 | 1.00 | — | — | |
| SCHEMBL1614979 | 0.96 | — | — | |
| SCHEMBL15670203 | 0.96 | — | — | |
| SCHEMBL23802808 | 0.96 | — | — | |
| SCHEMBL23802763 | 0.96 | — | — | |
| Bromide SCHEMBL15670239 | 0.93 | — | — | |
| SCHEMBL23126402 | 0.83 | — | — | |
| SCHEMBL21910170 | 0.83 | — | — | |
| SCHEMBL10979288 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627868-B1 | Aspartic ester functional compounds | BAYER MATERIALSCIENCE LLC (US) | 2007-12-19 | — | — | EP | claimed |
| CN-1865229-A | Aspartic ester functional compounds | BAYER MATERIALSCIENCE LLC (US) | 2006-11-22 | — | — | CN | claimed |
| EP-1627868-A2 | Aspartic ester functional compounds | Bayer MaterialScience LLC (US) | 2006-02-22 | — | — | EP | claimed |
| US-20060011295-A1 | Aspartic ester functional compounds | BAYER MATERIAL SCIENCE LLC | 2006-01-19 | — | — | US | claimed |
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-07-11 | — | — | US | disclosed |
| US-20230382923-A1 | FUSED TETRACYCLIC QUINAZOLINE DERIVATIVES AS INHIBITORS OF ERBB2 | ENLIVEN INC. | 2023-11-30 | — | — | US | disclosed |
| US-20230382923-A1 | FUSED TETRACYCLIC QUINAZOLINE DERIVATIVES AS INHIBITORS OF ERBB2 | ENLIVEN INC. | 2023-11-30 | — | — | US | disclosed |
| US-11807649-B2 | Fused tetracyclic quinazoline derivatives as inhibitors of ErbB2 | ENLIVEN THERAPEUTICS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-11807649-B2 | Fused tetracyclic quinazoline derivatives as inhibitors of ErbB2 | ENLIVEN THERAPEUTICS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| WO-2023178204-A1 | ENGINEERED ANTIBODIES AS MOLECULAR DEGRADERS THROUGH CELLULAR RECEPTORS | YALE UNIVERSITY (US) | 2023-09-21 | — | — | WO | disclosed |
| US-11739074-B2 | Ras inhibitors | Revolution Medicines, Inc. (US) | 2023-08-29 | — | — | US | disclosed |
| WO-2023141300-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| EP-0095906-B1 | IMPROVEMENTS RELATING TO COMPOUNDS USEFUL IN RADIOTHERAPY OR CHEMOTHERAPY | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-10-22 | — | — | EP | disclosed |
| US-4596817-A | Chemopotentiating agents | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-06-24 | — | — | US | disclosed |
| US-4581368-A | ANTICARCINOGENIC AGENT POTENTIATORS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-04-08 | — | — | US | disclosed |
| US-4578195-A | Process for the purification of effluents and purge streams containing trace elements | OLIN CORPORATION (US) | 1986-03-25 | — | — | US | disclosed |
| US-4518760-A | FROM A POLYIMINE AND A POLYISOCYANATE THROUGH A POLYAMINEPOLYUREA INTERMEDIATE, REACTED WITH AMMONIUM HYDROXIDE AND CARBON DISULFIDE | OLIN CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |
| EP-0095906-A1 | Improvements relating to compounds useful in radiotherapy or chemotherapy | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-12-07 | — | — | EP | disclosed |
| US-4337154-A | FORMED FROM A POLYALKYLENIMINE AND A NITROGEN-HETEROCYCLIC SECONDARY AMINE COMPOUND | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| US-3998808-A | INSECTICIDES, FUNGICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |