Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 11/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 10/20 | 0.56 |
| ▸ | IKBKB | O14920 | 1/20 | 0.54 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.52 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2572631 | 1.00 | MKNK1 (0.56) | MKNK1MKNK2IKBKBCHEK2F7 | |
| SCHEMBL30165669 | 1.00 | MKNK1 (0.56) | MKNK1MKNK2IKBKBCHEK2F7 | |
| SCHEMBL944036 | 0.88 | MKNK1 (0.47) | MKNK1MKNK2IKBKBCHEK2F7 | |
| SCHEMBL231896 | 0.86 | MKNK1 (0.56) | MKNK1MKNK2IKBKBCHEK2CYP3A4 | |
| SCHEMBL30292682 | 0.84 | MKNK1 (0.54) | MKNK1MKNK2IKBKBCHEK2 | |
| SCHEMBL12469057 | 0.84 | MKNK1 (0.54) | MKNK1MKNK2IKBKBCHEK2 | |
| SCHEMBL4560363 | 0.83 | MKNK1 (0.50) | MKNK1MKNK2IKBKBF7F3 | |
| SCHEMBL944217 | 0.82 | MKNK1 (0.51) | MKNK1MKNK2IKBKBCHEK2F7 | |
| SCHEMBL945200 | 0.82 | MKNK1 (0.51) | MKNK1MKNK2IKBKBCHEK2F7 | |
| SCHEMBL2228105 | 0.81 | MKNK1 (0.54) | MKNK1MKNK2IKBKBCHEK2F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151311-A1 | NICOTINAMIDE DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-07-17 | — | — | WO | disclosed |
| CN-115109048-B | (hetero) aryl amide compound | 中国药科大学 | 2023-12-08 | — | — | CN | disclosed |
| EP-4225310-A1 | HETEROARYL AMIDE INHIBITORS OF CD38 | Napa Therapeutics Ltd. (VG) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022077034-A1 | HETEROARYL AMIDE INHIBITORS OF CD38 | NAPA THERAPEUTICS LTD. (VG) | 2022-04-14 | — | — | WO | disclosed |