Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 20/20 | 0.55 |
| ▸ | KRAS | P01116 | 6/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25346470 | 1.00 | SOS1 (0.55) | SOS1KRASEGFR | |
| SCHEMBL25346476 | 1.00 | SOS1 (0.55) | SOS1KRASEGFR | |
| SCHEMBL29594027 | 0.92 | SOS1 (0.50) | SOS1KRASEGFR | |
| SCHEMBL20509925 | 0.92 | SOS1 (0.50) | SOS1KRASEGFR | |
| SCHEMBL20509924 | 0.92 | SOS1 (0.50) | SOS1KRASEGFR | |
| SCHEMBL20509504 | 0.91 | SOS1 (0.58) | SOS1KRASEGFR | |
| SCHEMBL20509503 | 0.91 | SOS1 (0.58) | SOS1KRASEGFR | |
| SCHEMBL29595204 | 0.91 | SOS1 (0.58) | SOS1KRASEGFR | |
| SCHEMBL20509101 | 0.82 | SOS1 (0.63) | SOS1KRASEGFR | |
| SCHEMBL20509103 | 0.82 | SOS1 (0.63) | SOS1KRASEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225383-A1 | MODULATORS OF CELL PROLIFERATION AND USES THEREOF | Kumquat Biosciences Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076917-A1 | MODULATORS OF CELL PROLIFERATION AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-04-14 | — | — | WO | disclosed |