SCHEMBL29595282

SCHEMBL29595282

C[SiH2]C1C(C)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
TSHR P16473 1/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KIF11 P52732 1/20 0.30
S1PR1 P21453 1/20 0.30
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28897066 0.97 BRD4 (0.32) BRD4CREBBP
SCHEMBL28897064 0.95 BRD4 (0.31) BRD4CREBBP
SCHEMBL22418974 0.92 BRD4 (0.34) BRD4CREBBPTSHRNPC1LMNA
SCHEMBL25272907 0.85 BRD4 (0.32) BRD4CREBBP
SCHEMBL21315886 0.82 BRD4 (0.30) BRD4CREBBP
SCHEMBL7036100 0.82 BRD4 (0.36) BRD4CREBBPTSHRNPC1LMNA
SCHEMBL22401711 0.81 BRD4 (0.32) BRD4CREBBP
SCHEMBL21002295 0.80 TSHR (0.36) BRD4CREBBPTSHRNPC1LMNA
SCHEMBL22401709 0.80 BRD4 (0.34) BRD4CREBBPTSHRNPC1LMNA
SCHEMBL29773661 0.80 TSHR (0.36) BRD4CREBBPTSHRNPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114401977-B Transition metal compound and catalyst composition comprising the same 株式会社LG化学 2024-08-02 CN disclosed
CN-114401977-A Transition metal compound and catalyst composition comprising the same 株式会社LG化学 2022-04-26 CN disclosed