Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 11/20 | 0.57 |
| ▸ | DCK | P27707 | 5/20 | 0.46 |
| ▸ | OXTR | P30559 | 2/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20303347 | 1.00 | CHRM4 (0.57) | CHRM4DCKOXTRAVPR1APDE3B | |
| SCHEMBL20302675 | 0.89 | CHRM4 (0.59) | CHRM4DCKOXTRAVPR1APDE3B | |
| SCHEMBL29595114 | 0.89 | CHRM4 (0.59) | CHRM4OXTRAVPR1APDE3BPDE3A | |
| SCHEMBL29594931 | 0.89 | CHRM4 (0.59) | CHRM4DCKOXTRAVPR1APDE3B | |
| SCHEMBL20302508 | 0.89 | CHRM4 (0.59) | CHRM4OXTRAVPR1APDE3BPDE3A | |
| SCHEMBL29595618 | 0.87 | CHRM4 (0.68) | CHRM4DCKOXTRAVPR1APDE3B | |
| SCHEMBL20302285 | 0.87 | CHRM4 (0.68) | CHRM4DCKOXTRAVPR1APDE3B | |
| SCHEMBL20321271 | 0.86 | CHRM4 (0.56) | CHRM4OXTRAVPR1APDE10APIK3CA | |
| SCHEMBL20302529 | 0.86 | CHRM4 (0.62) | CHRM4DCKOXTRAVPR1A | |
| SCHEMBL29595877 | 0.86 | CHRM4 (0.62) | CHRM4DCKOXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319298-B2 | Heteroaryl piperidine ether allosteric modulators of the M4 muscarinic acetylcholine receptor | MERCK SHARP & DOHME CORP. (US) | 2022-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319298-B2 | Heteroaryl piperidine ether allosteric modulators of the M4 muscarinic acetylcholine receptor | CHRM4, CHRM2, CHRM5 | CHRM4 1/4885DCK 2633/4885OXTR 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.