Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | DAO | P14920 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378260 | 1.00 | FLT3 (0.65) | FLT3KDM4EMAPTDAOHPGD | |
| Hydrochloric Acid SCHEMBL35211567 | 0.98 | FLT3 (0.62) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL25106917 | 0.86 | FLT3 (0.61) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL30944769 | 0.83 | KDM4E (0.60) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL3252732 | 0.83 | FLT3 (0.57) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL3246966 | 0.83 | PDGFRB (0.57) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL27254679 | 0.83 | KDM4E (0.60) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL1849662 | 0.83 | FLT3 (0.61) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL1850804 | 0.81 | FLT3 (0.59) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL4925117 | 0.81 | FLT3 (0.59) | FLT3KDM4EMAPTDAOHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555585-B | HPK1 inhibitors and uses thereof | 锐格药业公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-109153642-B | Indole and azaindole halogenated allylamine derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2022-05-17 | — | — | CN | disclosed |