⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28949183 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL5379755 | 0.97 | — | — | |
| SCHEMBL1605123 | 0.87 | — | — | |
| SCHEMBL1159185 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL11828791 | 0.84 | — | — | |
| SCHEMBL7828756 | 0.84 | CYP2C19 (0.42) | — | |
| Hydrochloric Acid SCHEMBL11819121 | 0.84 | CYP2C19 (0.37) | — | |
| SCHEMBL6908806 | 0.82 | CYP2C19 (0.41) | — | |
| SCHEMBL6907695 | 0.82 | CYP2C19 (0.41) | — | |
| SCHEMBL6914515 | 0.82 | CYP2C19 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121331-B | Phenoxy aromatic acid compounds with cyclopropyl and pharmaceutically acceptable salts thereof, and preparation methods and applications thereof | 华创合成制药股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-113121337-B | Phenoxyaromatic acid with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-114315508-B | Technological method for synthesizing cyclopropyl bromide | 大连双硼医药化工有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-113121337-A | Phenoxy aromatic acid with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-113121331-A | Phenoxy aromatic acid compound with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-110028441-A | A kind of fluoro- 2-(1- bromine cyclopropyl of 5-) pyridine synthetic method | 江苏工程职业技术学院 | 2019-07-19 | — | — | CN | claimed |
| CN-1009272-B | PREPN. OF CIS-AND 1R CIS-DIBROMO-CHRYSANTHEMYL CHLORIDE | UNIV NANKAI (CN) | 1990-08-22 | — | — | CN | claimed |
| CN-86107672-A | The preparation of cis and IR cis-dibromo chrysanthemic acid acyl chlorides | — | 1988-06-01 | — | — | CN | claimed |
| US-20250171469-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2025-05-29 | — | — | US | disclosed |
| WO-2025011610-A1 | AMIDE DERIVATIVE, AND COMPOSITION AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2025-01-16 | — | — | WO | disclosed |
| CN-119306790-A | Amide derivative, composition and use thereof | 深圳市塔吉瑞生物医药有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-115010616-B | Synthesis method of 1-aminocyclopropane hydrochloride | 常州锐博生物科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-113121331-B | Phenoxy aromatic acid compounds with cyclopropyl and pharmaceutically acceptable salts thereof, and preparation methods and applications thereof | 华创合成制药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-113121337-B | Phenoxyaromatic acid with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-0868182-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1998-10-07 | — | — | EP | disclosed |
| WO-1997041096-A1 | NEW VITAMIN D DERIVATIVES WITH CARBO- OR HETEROCYCLIC SUBSTITUENTS AT C-25, A PROCESS FOR THEIR PRODUCTION, INTERMEDIATE PRODUCTS AND THEIR USE FOR PRODUCING MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-11-06 | — | — | WO | disclosed |
| WO-1997023213-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-07-03 | — | — | WO | disclosed |
| WO-1997009983-A1 | PIPERIDINE DERIVATIVES AND PROCESSES FOR THEIR PRODUCTION | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-03-20 | — | — | WO | disclosed |
| EP-0738257-A1 | NEW METHOD FOR N-CYCLOPROPYLATION OF AROMATIC AMINES, AS WELL AS COMPOUNDS AND COMPOSITIONS OBTAINED | SOMFAI, Eva, Dr. (HU) | 1996-10-23 | — | — | EP | disclosed |
| WO-1995002573-A2 | NEW METHOD FOR N-CYCLOPROPYLATION OF AROMATIC AMINES, AS WELL AS COMPOUNDS AND COMPOSITIONS OBTAINED | SOMFAI EVA (HU) | 1995-01-26 | — | — | WO | disclosed |