Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29518581 | 0.93 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLHPGD | |
| SCHEMBL9565558 | 0.93 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLHPGD | |
| SCHEMBL1225718 | 0.93 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLHPGD | |
| SCHEMBL30668445 | 0.92 | KDM4E (0.48) | KDM4EKMT2AMEN1RECQLHPGD | |
| SCHEMBL6716587 | 0.88 | KDM4E (0.52) | KDM4EKMT2AMEN1RECQLHPGD | |
| SCHEMBL9513715 | 0.88 | KDM4E (0.52) | KDM4EKMT2AMEN1RECQLHPGD | |
| SCHEMBL10892005 | 0.88 | KDM4E (0.52) | KDM4EKMT2AMEN1RECQLHPGD | |
| SCHEMBL31279976 | 0.88 | KDM4E (0.52) | KDM4EKMT2AMEN1RECQLHPGD | |
| SCHEMBL9513712 | 0.88 | KDM4E (0.52) | KDM4EKMT2AMEN1RECQLHPGD | |
| SCHEMBL30136395 | 0.86 | TDP1 (0.44) | KDM4EKMT2AMEN1RECQLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203395-B | Organoleptic compounds | 国际香料和香精公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-108203622-B | Organoleptic compounds | 国际香料和香精公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-108203382-B | Novel organoleptic compounds | 国际香料和香精公司 | 2022-03-04 | — | — | CN | disclosed |