Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.64 |
| ▸ | PKD1 | P98161 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29600148 | 1.00 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL29600492 | 1.00 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL29600559 | 1.00 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL19899371 | 1.00 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL19899364 | 1.00 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL19899366 | 1.00 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL19899365 | 1.00 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL29599607 | 1.00 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL20929168 | 1.00 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL19899689 | 1.00 | MAP3K14 (0.64) | MAP3K14PKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863142-B | 2-azabicyclo [3.1.0] hex-3-one derivatives and methods of use | 豪夫迈·罗氏有限公司 | 2022-06-10 | — | — | CN | disclosed |