⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252068 | 0.93 | — | — | |
| SCHEMBL129752 | 0.86 | — | — | |
| SCHEMBL11875181 | 0.86 | — | — | |
| Methane SCHEMBL28272691 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL27463479 | 0.86 | — | — | |
| Benzene SCHEMBL28185882 | 0.76 | — | — | |
| Magnesium SCHEMBL31036680 | 0.57 | — | — | |
| SCHEMBL134850 | 0.57 | — | — | |
| Magnesium SCHEMBL31719611 | 0.54 | — | — | |
| SCHEMBL18583040 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585132-B | Proteasome activity enhancing compounds | 优曼尼蒂公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-113620944-B | Novel RET inhibitors, pharmaceutical compositions thereof and uses thereof | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-114222737-B | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-109863142-B | 2-azabicyclo [3.1.0] hex-3-one derivatives and methods of use | 豪夫迈·罗氏有限公司 | 2022-06-10 | — | — | CN | disclosed |