Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 7/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.44 |
| ▸ | CDC42BPB | Q9Y5S2 | 3/20 | 0.44 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1468800 | 1.00 | PIM2 (0.47) | PIM2PIM3PIM1ROCK2ROCK1 | |
| SCHEMBL1468799 | 1.00 | PIM2 (0.47) | PIM2PIM3PIM1ROCK2ROCK1 | |
| SCHEMBL1470547 | 1.00 | PIM2 (0.47) | PIM2PIM3PIM1ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL1468476 | 0.99 | PIM2 (0.46) | PIM2PIM3PIM1ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL1468479 | 0.99 | PIM2 (0.46) | PIM2PIM3PIM1ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL1469007 | 0.99 | PIM2 (0.46) | PIM2PIM3PIM1ROCK2ROCK1 | |
| SCHEMBL21468691 | 0.97 | HDAC1 (0.45) | PIM2PIM3PIM1ROCK2ROCK1 | |
| SCHEMBL1468677 | 0.95 | AAK1 (0.44) | PIM2PIM3PIM1ROCK2ROCK1 | |
| SCHEMBL1468679 | 0.95 | AAK1 (0.44) | PIM2PIM3PIM1ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL1468584 | 0.94 | AAK1 (0.44) | PIM2PIM3PIM1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11304939-B2 | Methods for treating oral cancers | CHANG GUNG UNIVERSITY (TW) | 2022-04-19 | — | — | US | claimed |
| CN-113667747-B | Method for treating oral cancer | 长庚大学 | 2025-01-24 | — | — | CN | disclosed |
| EP-3056210-B1 | DRUG FOR PREVENTION OR TREATMENT OF SPINOCEREBELLAR DEGENERATION | UNIV NAT CORP TOKYO MEDICAL & DENTAL (JP) | 2022-05-11 | — | — | EP | disclosed |