Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 0.76 |
| ▸ | ABL1 | P00519 | 10/20 | 0.76 |
| ▸ | EGFR | P00533 | 4/20 | 0.67 |
| ▸ | KDR | P35968 | 4/20 | 0.67 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.67 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.67 |
| ▸ | PRKDC | P78527 | 3/20 | 0.67 |
| ▸ | MTOR | P42345 | 3/20 | 0.67 |
| ▸ | HCK | P08631 | 3/20 | 0.67 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.67 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | LCK | P06239 | 2/20 | 0.64 |
| ▸ | FYN | P06241 | 2/20 | 0.64 |
| ▸ | YES1 | P07947 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408497 | 1.00 | SRC (0.76) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL409036 | 0.88 | SRC (0.80) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL409486 | 0.86 | SRC (1.00) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL13019676 | 0.85 | SRC (0.76) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL5620074 | 0.85 | SRC (0.78) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL409031 | 0.84 | SRC (1.00) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL130589 | 0.84 | PIK3CG (0.74) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL14617301 | 0.83 | SRC (0.89) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL3610160 | 0.82 | SRC (0.95) | SRCABL1EGFRKDRPIK3CD | |
| SCHEMBL1963186 | 0.81 | SRC (0.74) | SRCABL1EGFRKDRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| CN-110548032-B | Application of pyrazolopyrimidine compound in preparation of medicines for preventing/treating tumors | 四川大学华西医院 | 2023-05-05 | — | — | CN | disclosed |
| CN-110551130-B | Three-dimensional network structure crystal with high porosity and preparation method thereof | 四川大学华西医院 | 2022-04-19 | — | — | CN | disclosed |