SCHEMBL296002

SCHEMBL296002

C=CC(=O)NC(C)C(=O)CC(C)=O

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
ALDH1A1 P00352 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
MAPK1 P28482 1/20 0.37
ACACB O00763 2/20 0.33
CYP2C19 P33261 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8216369 0.79 TSHR (0.62) TSHRALDH1A1TDP1MAPK1ACACB
SCHEMBL4116841 0.79 TSHR (0.62) TSHRALDH1A1TDP1MAPK1ACACB
SCHEMBL7555507 0.78 TSHR (0.41) TSHRALDH1A1TDP1
SCHEMBL11358474 0.77 TSHR (0.50) TSHRALDH1A1TDP1MAPK1ACACB
SCHEMBL15226591 0.74 TSHR (0.62) TSHRALDH1A1TDP1MAPK1CYP2C19
SCHEMBL1647678 0.74 TSHR (0.62) TSHRALDH1A1TDP1MAPK1CYP2C19
SCHEMBL1081350 0.74 TSHR (0.62) TSHRALDH1A1TDP1MAPK1CYP2C19
SCHEMBL24492174 0.73 TSHR (0.56) TSHRALDH1A1TDP1MAPK1ACACB
SCHEMBL9502732 0.73 TSHR (0.56) TSHRALDH1A1TDP1MAPK1ACACB
SCHEMBL13275827 0.73 TSHR (0.50) TSHRALDH1A1TDP1MAPK1ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1682586-B1 AQUEOUS DISPERSIONS CONTAINING MULTI-STAGE EMULSION POLYMERS MOMENTIVE SPECIALTY CHEMICALS RES BELGIUM (BE) 2012-03-14 EP claimed
EP-1840136-B1 Polymer dispersions, method for their manufacture and their application CELANESE EMULSIONS GMBH (DE) 2010-08-11 EP claimed
EP-1682586-A4 AQUEOUS DISPERSIONS CONTAINING MULTI-STAGE EMULSION POLYMERS HEXION SPECIALTY CHEMICALS RES (BE) 2009-04-01 EP claimed
US-7445849-B2 Concrete moldings with a high gloss, their production and use CELANESE EMULSIONS GMBH (DE) 2008-11-04 US claimed
US-7285590-B2 Improved block resistance, low temperature film formation; emulsion copolymer with units of a ethylenically unsaturated nonionic monomers, strong acid and/or a weak acid, and a keto-group containing monomer; use in solvent-free gloss paints for example HEXION SPECIALTY CHEMICALS, INC. (US) 2007-10-23 US claimed
US-20070244238-A1 Polymer dispersions, process for the preparation thereof and the use thereof CELANESE EMULSIONS GMBH (DE) 2007-10-18 US claimed
EP-1840136-A2 Polymer dispersions, method for their manufacture and their application Celanese Emulsions GmbH (DE) 2007-10-03 EP claimed
EP-1518846-B1 Moulded concrete article having high gloss, method of making the same and use thereof CELANESE EMULSIONS GMBH (DE) 2007-04-18 EP claimed
EP-1147139-B1 AQUEOUS COPOLYMER DISPERSION, ITS METHOD OF PRODUCTION AND ITS USE CELANESE EMULSIONS GMBH (DE) 2006-09-06 EP claimed
EP-1682586-A2 AQUEOUS DISPERSIONS CONTAINING MULTI-STAGE EMULSION POLYMERS Hexion Specialty Chemicals Research Belgium S.A. (BE) 2006-07-26 EP claimed
WO-2005049184-A2 AQUEOUS DISPERSIONS CONTAINING MULTI-STAGE EMULSION POLYMERS RESOLUTION SPECIALTY MATERIALS LLC (US) 2005-06-02 WO claimed
US-20050107527-A1 Improved block resistance, low temperature film formation; emulsion copolymer with units of a ethylenically unsaturated nonionic monomers, strong acid and/or a weak acid, and a keto-group containing monomer; use in solvent-free gloss paints for example HEXION INC. (FORMERLY KNOWN AS MOMENTIVE SPECIALTY CHEMICALS INC.) 2005-05-19 US claimed
EP-1518846-A2 Moulded concrete article having high gloss, method of making the same and use thereof Celanese Emulsions GmbH (DE) 2005-03-30 EP claimed
US-20050064249-A1 Concrete moldings with a high gloss, their production and use CELANESE EMULSIONS GMBH (DE) 2005-03-24 US claimed
EP-1219650-A2 Star polymer colloidal stabilizers National Starch and Chemical Investment Holding Corporation (US) 2002-07-03 EP claimed
US-6005042-A HAVING A SPECIFIED RANGE OF GLASS TRANSITION TEMPERATURE PREPARED BY STEPWISE ADDITION POLYMERIZATION; SCRATCH RESISTANCT COATINGS CLARIANT GMBH (DE) 1999-12-21 US claimed
EP-1682586-B1 AQUEOUS DISPERSIONS CONTAINING MULTI-STAGE EMULSION POLYMERS MOMENTIVE SPECIALTY CHEMICALS RES BELGIUM (BE) 2012-03-14 EP disclosed
EP-1840136-B1 Polymer dispersions, method for their manufacture and their application CELANESE EMULSIONS GMBH (DE) 2010-08-11 EP disclosed
EP-0184091-B1 PROCESS FOR PREPARING POLYMER DISPERSIONS WHICH FORM BLOCKING-RESISTANT FILMS BASF Aktiengesellschaft (DE) 1989-11-08 EP disclosed
US-4654397-A MULTISTAGE ADDITION EMULSION POLYMERIZATION, UNSATURATED ACIDS OR AMIDES, FREE RADICAL CATALYST BASF AKTIENGESELLSCHAFT (DE) 1987-03-31 US disclosed