Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 16/20 | 0.63 |
| ▸ | NPY1R | P25929 | 10/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.63 |
| ▸ | NPY2R | P49146 | 6/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601388 | 0.99 | NPY4R (0.65) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL29600979 | 0.99 | NPY4R (0.65) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL31643144 | 0.93 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30712176 | 0.91 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2ROPRD1 | |
| SCHEMBL29462566 | 0.91 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2ROPRD1 | |
| SCHEMBL31053724 | 0.91 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31571458 | 0.90 | NPY4R (0.60) | NPY4RNPY1RNPY5RNPY2ROPRD1 | |
| SCHEMBL30420887 | 0.90 | NPY4R (0.66) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30799948 | 0.89 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31053730 | 0.89 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2ROPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605522-A | MCL-1 and BCL-XL protein dual-targeting BH3 polypeptide mimics and application thereof | 中山大学 | 2022-06-10 | — | — | CN | claimed |