Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | HAT1 | O14929 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12479995 | 1.00 | PBRM1 (0.54) | PBRM1CYP2C19KDM4EMAP2K1HSD17B10 | |
| SCHEMBL29600892 | 0.84 | TET2 (0.51) | CYP2C19KDM4EPARP1PSMD14MAPT | |
| SCHEMBL2816680 | 0.84 | TET2 (0.51) | CYP2C19KDM4EPARP1PSMD14MAPT | |
| Hydrochloric Acid SCHEMBL2040536 | 0.83 | TET2 (0.50) | CYP2C19KDM4EPARP1PSMD14MAPT | |
| SCHEMBL30436129 | 0.83 | PARP1 (0.58) | CYP2C19KDM4EPARP1PSMD14L3MBTL1 | |
| SCHEMBL1474939 | 0.83 | PARP1 (0.58) | CYP2C19KDM4EPARP1PSMD14L3MBTL1 | |
| SCHEMBL15389085 | 0.82 | MAP2K1 (0.61) | KDM4EMAP2K1PSMD14MAPTTDP1 | |
| SCHEMBL31753964 | 0.82 | MAP2K1 (0.61) | KDM4EMAP2K1PSMD14MAPTTDP1 | |
| SCHEMBL6432355 | 0.81 | CYP2C19 (0.49) | PBRM1CYP2C19KDM4EMAP2K1PARP1 | |
| Potassium Ion SCHEMBL7064340 | 0.80 | CYP2C19 (0.46) | PBRM1CYP2C19KDM4EMAP2K1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109061-A | Tricyclic compounds | 北京加科思新药研发有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-112513041-B | Tricyclic compounds | 北京加科思新药研发有限公司 | 2022-05-10 | — | — | CN | disclosed |