Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.73 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.73 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.69 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.67 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.67 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.67 |
| ▸ | MBD2 | Q9UBB5 | 2/20 | 0.66 |
| ▸ | MECP2 | P51608 | 1/20 | 0.66 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.65 |
| ▸ | KDM4A | O75164 | 3/20 | 0.62 |
| ▸ | KDM4B | O94953 | 2/20 | 0.62 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.62 |
| ▸ | KDM5C | P41229 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29078754 | 1.00 | CSNK2A2 (0.73) | CSNK2A2CSNK2BCSNK2A1KCNN1KCNN2 | |
| Bromide SCHEMBL29601604 | 0.99 | CSNK2A2 (0.71) | CSNK2A2CSNK2BCSNK2A1KCNN1KCNN2 | |
| SCHEMBL24358066 | 0.89 | KCNN1 (0.65) | CSNK2A2CSNK2BCSNK2A1KCNN1KCNN2 | |
| SCHEMBL30518671 | 0.89 | KCNN1 (0.65) | CSNK2A2CSNK2BCSNK2A1KCNN1KCNN2 | |
| SCHEMBL24358259 | 0.86 | KCNN1 (0.58) | CSNK2A2CSNK2BCSNK2A1KCNN1KCNN2 | |
| SCHEMBL30745673 | 0.86 | KCNN1 (0.58) | CSNK2A2CSNK2BCSNK2A1KCNN1KCNN2 | |
| SCHEMBL24358136 | 0.85 | KCNN1 (0.64) | CSNK2A2CSNK2BCSNK2A1KCNN1KCNN2 | |
| SCHEMBL29601651 | 0.85 | KCNN1 (0.64) | CSNK2A2CSNK2BCSNK2A1KCNN1KCNN2 | |
| SCHEMBL27039795 | 0.85 | KCNN1 (0.62) | CSNK2A2CSNK2BCSNK2A1KCNN1KCNN2 | |
| SCHEMBL24358274 | 0.84 | KCNN1 (0.56) | CSNK2A2CSNK2BCSNK2A1KCNN1KCNN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232449-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-116547282-A | Heterocyclic compounds and their use for the treatment of helminth infections and diseases | 新基公司 | 2023-08-04 | — | — | CN | disclosed |
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |