Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN1 | Q92952 | 2/20 | 1.00 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 1.00 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 1.00 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.73 |
| ▸ | MEN1 | O00255 | 11/20 | 0.73 |
| ▸ | NPC1 | O15118 | 10/20 | 0.73 |
| ▸ | RAB9A | P51151 | 9/20 | 0.73 |
| ▸ | CASP3 | P42574 | 2/20 | 0.73 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.73 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.73 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.73 |
| ▸ | MECP2 | P51608 | 1/20 | 0.72 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.67 |
| ▸ | RELA | Q04206 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157963 | 1.00 | KCNN1 (1.00) | KCNN1KCNN2KCNN3SLC2A1KMT2A | |
| SCHEMBL14743426 | 0.90 | KCNN1 (0.82) | KCNN1KCNN2KCNN3SLC2A1KMT2A | |
| SCHEMBL29497622 | 0.90 | KCNN1 (0.82) | KCNN1KCNN2KCNN3SLC2A1KMT2A | |
| SCHEMBL5173768 | 0.89 | KCNN1 (0.80) | KCNN1KCNN2KCNN3SLC2A1KMT2A | |
| SCHEMBL29601174 | 0.89 | KCNN1 (0.80) | KCNN1KCNN2KCNN3SLC2A1KMT2A | |
| SCHEMBL24358078 | 0.86 | KCNN1 (0.76) | KCNN1KCNN2KCNN3SLC2A1KMT2A | |
| SCHEMBL24358084 | 0.86 | MEN1 (0.80) | KCNN1KCNN2KCNN3SLC2A1KMT2A | |
| SCHEMBL6368980 | 0.86 | KCNN1 (0.75) | KCNN1KCNN2KCNN3SLC2A1KMT2A | |
| SCHEMBL24357992 | 0.86 | KCNN1 (0.75) | KCNN1KCNN2KCNN3SLC2A1KMT2A | |
| SCHEMBL30745697 | 0.86 | KCNN1 (0.75) | KCNN1KCNN2KCNN3SLC2A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232449-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |