Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22824017 | 1.00 | PTGDR2 (0.49) | PTGDR2LRRK2MAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL29367739 | 1.00 | PTGDR2 (0.49) | PTGDR2LRRK2MAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL29602040 | 0.89 | PTGDR2 (0.38) | PTGDR2LRRK2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22823739 | 0.89 | PTGDR2 (0.38) | PTGDR2LRRK2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22824021 | 0.85 | PTGDR2 (0.52) | PTGDR2LRRK2MAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL29602362 | 0.85 | PTGDR2 (0.52) | PTGDR2LRRK2MAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL22824018 | 0.81 | PTGDR2 (0.42) | PTGDR2ALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL28696816 | 0.81 | PTGDR2 (0.42) | PTGDR2ALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL29368651 | 0.81 | PTGDR2 (0.42) | PTGDR2ALDH1A1SMN1; SMN2MEN1TSHR | |
| SCHEMBL22824019 | 0.81 | PTGDR2 (0.46) | PTGDR2LRRK2ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986852-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD Pharma A/S (DK) | 2022-04-27 | — | — | EP | disclosed |