Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 7/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29602337 | 0.93 | MCL1 (0.37) | MCL1MTNR1AMTNR1BBCL2BCL2L1 | |
| SCHEMBL29602389 | 0.87 | MCL1 (0.40) | MCL1BCL2BCL2L1 | |
| SCHEMBL19615113 | 0.82 | MCL1 (0.55) | MCL1BCL2BCL2L1 | |
| SCHEMBL29602384 | 0.81 | HRH3 (0.40) | MCL1BCL2BCL2L1HTR2A | |
| SCHEMBL19635136 | 0.80 | MCL1 (0.46) | MCL1BCL2BCL2L1 | |
| SCHEMBL19615175 | 0.75 | MCL1 (0.55) | MCL1BCL2BCL2L1 | |
| SCHEMBL19635426 | 0.74 | MCL1 (0.47) | MCL1BCL2BCL2L1 | |
| SCHEMBL29602000 | 0.72 | MCL1 (0.48) | MCL1BCL2BCL2L1 | |
| SCHEMBL19615275 | 0.69 | MCL1 (0.60) | MCL1BCL2BCL2L1 | |
| SCHEMBL29602219 | 0.69 | MCL1 (0.60) | MCL1BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458459-B1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AG (DE) | 2022-04-27 | — | — | EP | claimed |