SCHEMBL29604209

SCHEMBL29604209

OCc1cc(-c2ccc(F)c(C(F)F)c2)cnc1OC(F)F

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 20/20 0.44
GRIN2B Q13224 20/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22770784 1.00 GRIN1 (0.44) GRIN1GRIN2B
SCHEMBL22787234 0.87 GRIN1 (0.47) GRIN1GRIN2B
Hydrochloric Acid SCHEMBL22770902 0.86 GRIN1 (0.46) GRIN1GRIN2B
Hydrochloric Acid SCHEMBL29603445 0.86 GRIN1 (0.46) GRIN1GRIN2B
SCHEMBL22770918 0.81 GRIN2B (0.47) GRIN1GRIN2B
SCHEMBL29603450 0.81 GRIN2B (0.47) GRIN1GRIN2B
SCHEMBL29604000 0.79 GRIN1 (0.56) GRIN1GRIN2B
SCHEMBL22770991 0.79 GRIN1 (0.56) GRIN1GRIN2B
SCHEMBL29603911 0.77 LRRK2 (0.43) GRIN1GRIN2B
SCHEMBL22770958 0.76 GRIN2B (0.43) GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3983074-A1 PYRIDINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS Janssen Pharmaceutica NV (BE) 2022-04-20 EP disclosed