Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 18/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 15/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29604273 | 0.89 | GRIN1 (0.44) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL22770938 | 0.81 | GRIN1 (0.56) | GRIN2BGRIN1 | |
| SCHEMBL29603702 | 0.81 | GRIN1 (0.56) | GRIN2BGRIN1 | |
| SCHEMBL29603710 | 0.80 | GRIN1 (0.64) | GRIN2BGRIN1 | |
| SCHEMBL22770778 | 0.80 | GRIN1 (0.64) | GRIN2BGRIN1 | |
| SCHEMBL22787261 | 0.79 | GRIN2B (0.50) | GRIN2BGRIN1KCNH2 | |
| Hydrochloric Acid SCHEMBL22770963 | 0.78 | GRIN2B (0.49) | GRIN2BGRIN1KCNH2 | |
| Hydrochloric Acid SCHEMBL29603966 | 0.78 | GRIN2B (0.49) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL29603911 | 0.74 | LRRK2 (0.43) | GRIN2BGRIN1 | |
| SCHEMBL22770770 | 0.70 | GRIN1 (0.61) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983074-A1 | PYRIDINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | claimed |
| EP-3983074-A1 | PYRIDINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | disclosed |