Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 1.00 |
| ▸ | CYP2A13 | Q16696 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29604076 | 0.98 | CXCR4 (0.96) | CXCR4CYP2A13ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29604752 | 0.98 | CXCR4 (0.96) | CXCR4CYP2A13ALDH1A1MEN1KMT2A | |
| SCHEMBL13273494 | 0.91 | CXCR4 (0.83) | CXCR4CYP2A13ALDH1A1MEN1KMT2A | |
| SCHEMBL22304486 | 0.91 | CXCR4 (0.83) | CXCR4CYP2A13ALDH1A1MEN1KMT2A | |
| SCHEMBL946921 | 0.91 | CXCR4 (0.83) | CXCR4CYP2A13ALDH1A1MEN1KMT2A | |
| SCHEMBL4547964 | 0.88 | CXCR4 (0.77) | CXCR4CYP2A13ALDH1A1MEN1KMT2A | |
| SCHEMBL31372331 | 0.88 | CXCR4 (0.77) | CXCR4CYP2A13ALDH1A1MEN1KMT2A | |
| SCHEMBL13273129 | 0.88 | CXCR4 (0.77) | CXCR4CYP2A13ALDH1A1MEN1KMT2A | |
| SCHEMBL465778 | 0.88 | CXCR4 (0.77) | CXCR4CYP2A13ALDH1A1MEN1KMT2A | |
| SCHEMBL465823 | 0.88 | CXCR4 (0.77) | CXCR4CYP2A13ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11517565-B2 | Bis-amines, compositions, and uses related to CXCR4 inhibition | EMORY UNIVERSITY (US) | 2022-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11517565-B2 | Bis-amines, compositions, and uses related to CXCR4 inhibition | CXCR4, CXCL12, CXCR2 | CXCR4 1/4885CYP2A13 3089/4885ALDH1A1 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.