⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960478 | 1.00 | — | — | |
| SCHEMBL2956038 | 0.86 | KCNA3 (0.44) | — | |
| SCHEMBL28960037 | 0.85 | PDCD1 (0.44) | — | |
| SCHEMBL28960041 | 0.81 | PDCD1 (0.49) | — | |
| SCHEMBL31322323 | 0.80 | — | — | |
| SCHEMBL1361943 | 0.79 | — | — | |
| SCHEMBL9912480 | 0.79 | — | — | |
| SCHEMBL9912445 | 0.79 | — | — | |
| SCHEMBL14566805 | 0.78 | KCNA3 (0.40) | — | |
| SCHEMBL2893257 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268868-B2 | 5-pyridinone substituted indazoles | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100105679-A1 | 5-PYRIDINONE SUBSTITUTED INDAZOLES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-04-29 | — | — | US | disclosed |