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Sugi Predict / Compounds / SCHEMBL29605918

SCHEMBL29605918

SCHEMBL29605918

Cc1cc(C(=O)Nc2cccc(C3(c4nncn4C)CC(C)C3)c2)nc(C2CC2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 1.00
▸ CBLC Q9ULV8 1/20 0.48
▸ CBL P22681 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22832453 1.00 CBLB (1.00) CBLBCBLCCBL
SCHEMBL22849971 1.00 CBLB (1.00) CBLBCBLCCBL
SCHEMBL22832452 1.00 CBLB (1.00) CBLBCBLCCBL
SCHEMBL30577590 0.80 CBLB (0.67) CBLBCBLCCBL
SCHEMBL30625443 0.80 CBLB (0.66) CBLBCBLCCBL
SCHEMBL30625566 0.80 CBLB (0.66) CBLBCBLCCBL
SCHEMBL30625473 0.80 CBLB (0.66) CBLBCBLCCBL
SCHEMBL21200852 0.79 CBLB (0.70) CBLB
SCHEMBL29866670 0.79 CBLB (0.70) CBLB
SCHEMBL25360404 0.79 CBLB (0.65) CBLBCBLCCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114364670-B Substituted benzyl-triazole compound for Cbl-b inhibition and further application thereof 纽力克斯治疗公司 2025-06-13 — — CN disclosed
EP-3990117-A1 SUBSTITUTED BENZYL-TRIAZOLE COMPOUNDS FOR CBL-B INHIBITION, AND FURTHER USES THEREOF Nurix Therapeutics, Inc. (US) 2022-05-04 — — EP disclosed
CN-114364670-A Substituted benzyl-triazoles for Cbl-b inhibition and further uses thereof 纽力克斯治疗公司 2022-04-15 — — CN disclosed
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